Characterizing cargoes of the TPLATE complex: focus on Callose Synthases (GSLs) and Secretory Carrier Membrane Proteins (SCAMPs)

07 October 2023 → 06 June 2024
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Cell signaling
    • Membrane structure and transport
    • Plant cell and molecular biology
    • Plant developmental and reproductive biology
    • Proteomics
ABA callose male sterility Protein trafficking drought resistance endocytosis
Project description
Clathrin-mediated endocytosis internalizes plasma membrane proteins to react to various stimuli. In plants, the TPLATE complex plays a crucial role in this, but how it recognizes its cargo remains unknown. This project mechanistically investigates the trafficking of two proteins: SCAMP and Callose Synthase, both known cargoes of the TPLATE complex. Furthermore, this project will address how internalization controls their function.