Research Explorer

Project

Dose de-escalation to the elective nodal sites, the swallouwing apparatus and neck soft tissues for had and neck cancer: multi-centre, randomized phase III trial using image-guided intensity-modulated radiotherapy (IG-IMRT)
Code
365G1208
Duration
01 January 2008 → 31 December 2010
Funding
Funding by bilateral agreement (private and foundations)
Research disciplines
  • Medical and health sciences
    • Medical imaging and therapy
    • Morphological sciences
    • Oncology
    • Medical imaging and therapy
    • Morphological sciences
    • Oncology
    • Other paramedical sciences
    • Medical imaging and therapy
    • Morphological sciences
    • Oncology
Keywords
dysphagia fibrosis radiation therapy
 
Project description

Dysphagia and neck fibrosis are caused by high radiation doses delivered to the neck, the pharyngeus constrictor muscles and the cervical esophagus. The present randomized trial aims at reducing these side effects by selective dose de-escalation on radiation sensitive structuresin the neck. De-escalation is made possible by IG-IMRT. UZLeuven, UZGent, UZBrussel en UZAntwerpen collaborate to conduct this trial.