Code
01SC1514
Duration
01 March 2014 → 30 September 2017
Funding
Regional and community funding: Special Research Fund
Promotor
Fellow
Research disciplines
-
Medical and health sciences
- Biomarker discovery and evaluation
- Drug discovery and development
- Medicinal products
- Pharmaceutics
- Pharmacognosy and phytochemistry
- Pharmacology
- Pharmacotherapy
- Toxicology and toxinology
- Other pharmaceutical sciences
-
Engineering and technology
- Biomaterials engineering
- Ceramic and glass materials
- Materials science and engineering
- Semiconductor materials
- Other materials engineering
- Biological system engineering
- Biomaterials engineering
- Biomechanical engineering
- Other (bio)medical engineering
- Environmental engineering and biotechnology
- Industrial biotechnology
- Other biotechnology, bio-engineering and biosystem engineering
Keywords
polymers
vaccines
microparticles
Project description
Formulating vaccine antigens in particulate rather than soluble form strongly enhances the induction of cellular immunity. However, there is a big demand for strategies that allow for the formulation of vaccine antigens into microparticles under mild benign conditions. In this project we aim to develop a microparticulate vaccine formulation based on polymeric particles, encapsulating the vaccine antigens, that are stabilized via hydrogen bonding.