Project

A comprehensive evaluation of qPCR and antibody-ELISA to assess the interruption of transmission of soil-transmitted helminth infections

Code
01W07020
Duration
01 October 2020 → 09 June 2021
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Preventive medicine
    • Public health services not elsewhere classified
    • Diagnostics not elsewhere classified
    • Parasitology
    • Tropical medicine not elsewhere classified
Keywords
soil-transmitted helminths Ascaris Trichuris hookworms stool serum antibody - ELISA qPCR interruption of disease transmission large-scale deworming programs
 
Project description

Large-scale deworming programs against soil-transmitted helminths (STH) are moving from morbidity control towards interruption of STH transmission. However, there are currently few diagnostic tools that may reliably inform the program when to stop the administration of drugs. We will evaluate qPCR and anti-body ELISAs as diagnostic tools to assess the interruption of STH transmission.