Research Explorer

Project

Laser induced vapour nanobubbles as a novel therapeutic approach for treating biofilm-related infections
Code
01G02215
Duration
01 January 2015 → 31 December 2021
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Immunology
    • Medical imaging and therapy
    • Immunology
    • Medical imaging and therapy
    • Microbiology
    • Other paramedical sciences
    • Biomarker discovery and evaluation
    • Drug discovery and development
    • Medicinal products
    • Pharmaceutics
    • Pharmacognosy and phytochemistry
    • Pharmacology
    • Pharmacotherapy
    • Toxicology and toxinology
    • Other pharmaceutical sciences
    • Immunology
    • Medical imaging and therapy
Keywords
biophotonics biofilms nanomedicines
 
Project description
 

Biofilms are consortia of micro-organisms that cause e.g. wound and dental root canal infections. One important reason for the decreased sensitivity of cells in a biofilm to antimicrobial agents is hindered transport of drugs. This project aims at improving drug transport by disrupting the biofilm structure through laser induced vapour nanobubbles and by incorporating antimicrobial drugs in nanomedicine carriers.