Code
01P04012
Duration
01 October 2012 → 01 October 2014
Funding
Regional and community funding: Special Research Fund
Promotor
Research disciplines
-
Natural sciences
- Animal biology
- Microbiology
- Systems biology
-
Medical and health sciences
- Gastro-enterology and hepatology
- Immunology
- Laboratory medicine
- Microbiology
- Gastro-enterology and hepatology
- Immunology
- Laboratory medicine
- Microbiology
- Gastro-enterology and hepatology
- Immunology
- Laboratory medicine
- Microbiology
-
Agricultural and food sciences
- Veterinary medicine
- Other veterinary sciences
- Other agricultural, veterinary and food sciences
Keywords
helicobacter suis
gammaglutamyl transpeptidase
immune modulation
virulence mechanisms
cell necrosis
Project description
Helicobacter suis is the most prevalent non-Helicobacter pylori Helicobacter species in humans suffering from gastric disease. We aim to unravel the mechanisms used by this bacterium and its gamma-glutamyl transpeptidase to cause gastric epithelial cell death on one hand and to modulate the host immune response on the other hand.