Research Explorer

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Project

An integrated approach to unravel eosinophil function in chronic eosinophilic disorders

Outputs & Impact

Publications & research data ( 36 )

GM-CSF and specific type 2 cytokines induce CD103+and CD301b+cell states in cDC1s and cDC2s

Lukas AmonDamir VurnekAnna SeichterGiorgi TchitashviliTomasz KaszubowskiMarkus MrozNincy DebeufTina VoglerNicole KuepperKaushikk Ravi Rengarajan et al.

A1 Journal Article in CELL REPORTS

Mechanisms and kinetics of wound healing in chronic rhinosinusitis patients after complete sinus surgery and its improvement by doxycycline therapy

Elke VandewalleEls De SchryverLien CalusManon BlauwblommePauline JanssenEllen KetelaereSharon Van NevelAnne-Sophie EeckelsNatalie De RuyckGabriële Holtappels et al.

A1 Journal Article in INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY

Type‐2 biomarkers, asthma diagnosis and lung function impairment in the general population

Sebastian RiemannAndrei MalinovschiGuy Brusselle

A1 Journal Article in CLINICAL AND EXPERIMENTAL ALLERGY

Biologics in severe asthma : unmasking EGPA along the way

Virginie Van HeckSebastian RiemannGuy Brusselle

Editorial material

Functional humoral response during intranasal convalescent plasma prophylaxis for severe acute respiratory syndrome coronavirus 2

Caro VerbruggheRana AbdelnabiTania MaesLotte CoelmontBirgit WeynandPhilippe VandekerckhoveJohan NeytsHendrik FeysElise Wouters

A1 Journal Article in JOURNAL OF INFECTIOUS DISEASES

Targeting γc family cytokines with biologics : current status and future prospects

Fabian BickChristophe BlanchetotBart LambrechtMartijn Schuijs

A1 Journal Article in MABS

A genetically encoded endogenous antibody recruitment strategy for innate immune-mediated killing of cancer cells

Justine AelvoetZifu ZhongClaudia Mariela Brenis GómezHelena Catharine AegerterBenoit LouageBart LambrechtBruno De GeestMartijn Schuijs

A1 Journal Article in ADVANCED MATERIALS

Anti-IL-5 treatment, but not neutrophil interference, attenuates inflammation in a mixed granulocytic asthma mouse model, elicited by air pollution

Joyceline De VolderAnnelies BontinckValerie HaeltermanLouis BoonGuy JoosGuy BrusselleTania Maes

A1 Journal Article in RESPIRATORY RESEARCH

Unraveling inflammatory responses in pollutant-aggravated allergic asthma

Joyceline De VolderTania MaesGuy Brusselle

Small-angle X-ray scattering of engineered antigen-binding fragments : the case of glycosylated Fab from the Mannitou IgM antibody

Shubham SemwalMaria KaramolegkouStéphanie FlamentNessim RaouraouaKenneth VerstraeteAurélien ThureauFrank WienFabrice BraySavvas SavvidesJulie Bouckaert

A1 Journal Article in ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS

A reappraisal of IL-9 in inflammation and cancer

Fabian BickChristophe BlanchetotBart LambrechtMartijn Schuijs

A1 Journal Article in MUCOSAL IMMUNOLOGY

Physicochemical and biological stability of diluted vedolizumab in intravenous infusion bags

Tine C. J. HendrickxKevin BalcaenMarielle BaertJurgen HaustraeteBart Lambrecht

A1 Journal Article in EUROPEAN JOURNAL OF HOSPITAL PHARMACY

Efficacy of biologics in NSAID-ERD : united airways from the nose to the bronchi

Kathleen M. BuchheitElke VandewalleHester B.E. ElzingaSietze ReitsmaWytske FokkensPhilippe Gevaert

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE

TCR transgenic clone selection guided by immune receptor analysis and single-cell RNA expression of polyclonal responders

Nincy DebeufSahine LameireManon VanheerswynghelsJulie DeckersCaroline De WolfWendy ToussaintRein VerbekeKevin VerstaenHamida HammadStijn Vanhee et al.

A2 Journal Article in ELIFE

Repeated COVID-19 mRNA-based vaccination contributes to SARS-CoV-2 neutralizing antibody responses in the mucosa

Jozefien DeclercqSarah GerloSharon Van NevelNatalie De RuyckGabriële HoltappelsLiesbeth DelesieEls TobbackInés LammensNikita GerebtsovKoen Sedeyn et al.

A1 Journal Article in SCIENCE TRANSLATIONAL MEDICINE

Inhaled GM-CSF administered during ongoing pneumovirus infection alters myeloid and CD8 T cell immunity without affecting disease outcome

Nincy DebeufJulie DeckersSahine LameireCedric BosteelsHamida HammadBart Lambrecht

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Case report : dual monoclonal antibody therapy in chronic rhinosinusitis with nasal polyps and severe eosinophilic asthma : a proteome analysis

Manon BlauwblommePhilippe GevaertSharon Van NevelSebastian RiemannElke VandewalleGabriële HoltappelsNatalie De RuyckLara DeryckeAnne-Sophie EeckelsStijn Vanhee et al.

A2 Journal Article in FRONTIERS IN ALLERGY

Interleukin-33-activated basophils promote asthma by regulating Th2 cell entry into lung tissue

Martijn SchuijsClaudia Mariela Brenis GómezFabian BickJustine Van MoorleghemManon VanheerswynghelsGeert van LooRudi BeyaertDavid VoehringerRichard M. LocksleyHamida Hammad et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

Single-cell proteomics and transcriptomics capture eosinophil development and identify the role of IL-5 in their lineage transit amplification

Joseph JorssenGlenn Van HulstKirena MollersJulien PujolGeorgios PetrellisAntonio Pires da Silva BaptistaSjoerd SchettersFrederic BaronJo CaersBart Lambrecht et al.

A1 Journal Article in IMMUNITY

IL-2 family cytokines IL-9 and IL-21 differentially regulate innate and adaptive type 2 immunity in asthma

Fabian BickClaudia Mariela Brenis GómezInés LammensJustine Van MoorleghemCaroline De WolfSam DupontLaure DumoutierNeal P. SmithAlexandra-Chloé VillaniRobin Browaeys et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Sublingual allergen immunotherapy prevents house dust mite inhalant type 2 immunity through dendritic cell-mediated induction of Foxp3+ regulatory T cells

Katrien Van Der BorghtJens BrimnesEline HaspeslaghStephanie BrandKatrijn NeytShashank GuptaNiels Peter Hell KnudsenHamida HammadPeter S. AndersenBart Lambrecht

A1 Journal Article in MUCOSAL IMMUNOLOGY

Evaluating β2-agonists as siRNA delivery adjuvants for pulmonary surfactant-coated nanogel inhalation therapy

Pieterjan MerckxGRIET CONICKXEvy BlommeTania MaesKen BrackeGuy BrusselleStefaan De SmedtKoen Raemdonck

A1 Journal Article in EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Ym1 protein crystals promote type 2 immunity

Ines HeyndrickxKim DeswarteKenneth VerstraeteKoen VerschuerenUrsula SmoleHelena Catharine AegerterAnn DansercoerHamida HammadSavvas SavvidesBart Lambrecht

A1 Journal Article in ELIFE

Aspergillus and the lung

Iris JanssensBart LambrechtEva Van Braeckel

A1 Journal Article in SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Activation of goblet-cell stress sensor IRE1β is controlled by the mucin chaperone AGR2

Eva ClootsPhaedra GuilbertMathias ProvostLisa NeidhardtEvelien Van De VeldeFarzaneh FayazpourDelphine De SutterSavvas SavvidesSven EyckermanSophie Janssens

A1 Journal Article in EMBO JOURNAL

Trajectory of neutrophilic responses in a mouse model of pollutant-aggravated allergic asthma

Joyceline De VolderAnnelies BontinckKatrien De GroveIris DirvenValerie HaeltermanGuy JoosGuy BrusselleTania Maes

A1 Journal Article in ENVIRONMENTAL POLLUTION

Protein citrullination and NET formation do not contribute to the pathology of A20/TNFAIP3 mutant mice

Karel Van DammePieter HertensArne MartensElisabeth GilisDario PriemInge BruggemanAmelie FossoulJozefien DeclercqHelena Catharine AegerterAndy Wullaert et al.

A1 Journal Article in SCIENTIFIC REPORTS

CCL5-producing migratory dendritic cells guide CCR5+ monocytes into the draining lymph nodes

Kavita RawatAnita TewariXin LiArlind B. B. MaraWilliam T. T. KingSophie L. L. GibbingsChinaza F. F. NnamFred W. W. KollingBart LambrechtClaudia V. V. Jakubzick

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

Chitinases and chitinase-like proteins in asthma

Jozefien DeclercqHamida HammadBart LambrechtUrsula Smole

A1 Journal Article in SEMINARS IN IMMUNOLOGY

STE20 kinase TAOK3 regulates type 2 immunity and metabolism in obesity

Bastiaan MaesFarzaneh FayazpourLeen CatrysseGuillaume LornetEvelien Van De VeldeCaroline De WolfSofie De PrijckJustine Van MoorleghemManon VanheerswynghelsKim Deswarte et al.

A1 Journal Article in JOURNAL OF EXPERIMENTAL MEDICINE

Mepolizumab attenuates ILC2s proliferation and activity in adults with severe eosinophilic asthma

Guy BrusselleSebastian RiemannTania Maes

Editorial material

RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD

Hannelore Van EeckhoutteChantal DonovanRichard Y. KimThomas M. ConlonMeshal AnsariHaroon KhanRanjith JayaramanNicole G. HansbroYves DondelingerTom Delanghe et al.

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

Pore-forming proteins as drivers of membrane permeabilization in cell death pathways

Peter VandenabeeleGeert BultynckSavvas Savvides

A1 Journal Article in NATURE REVIEWS MOLECULAR CELL BIOLOGY

Biology of lung macrophages in health and disease

Helena Catharine AegerterBart LambrechtClaudia V. Jakubzick

A1 Journal Article in IMMUNITY

The STE20 kinase TAOK3 controls the development of house dust mite-induced asthma in mice

Bastiaan MaesUrsula SmoleMatthias VanderkerkenKim DeswarteJustine Van MoorleghemKarl VergoteManon VanheerswynghelsCaroline De WolfSofie De PrijckNincy Debeuf et al.

A1 Journal Article in JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Simultaneous inhibition of thymic stromal lymphopoietin, IL-33 and IL-25 : a therapeutic option in asthma?

Tania MaesGuy Brusselle

Editorial material

Activities ( 0 )

Results

Impact narratives ( 1 )

Medicine: allergy

Area(s): Health

Patents ( 0 )