Project

Exploring the Nlrp6 interactome and its role in immune signaling

Code
01J11113
Duration
01 March 2013 → 31 December 2017
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Biochemistry and metabolism
    • Systems biology
  • Medical and health sciences
    • Immunology
    • Medical biochemistry and metabolism
    • Immunology
    • Medical biochemistry and metabolism
    • Immunology
    • Medical biochemistry and metabolism
Keywords
NOD-like receptor Nlrp6 inflammasome
 
Project description

To characterize the activation mechanisms, interactomes and molecular functions of Nlrp6, I will use targeted approaches designed to map the activation mechanisms of hte Nlrp6 inflammasome, and to characterize the molecular role of Nlrp6 and its interaction partners in immune signalling pathways.