Project

Ultramicroscopic and molecular characteristics of the initial steps in intususceptive angiogensis: potential role of the angiopoietins and their receptors.

Duration
01 January 2013 → 31 October 2017
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Animal biology
    • Genetics
  • Agricultural and food sciences
    • Veterinary medicine
Keywords
ultramicroscopy glomerulogenesis angiogenesis
 
Project description

Ultramicroscopic three-dimensional investigation of the initial steps of intussusceptive angiogenesis during glomerulogenesis in the porcine embryonic kidney. The morphological features are combined with the immunohistochemical detection and cellular localization (through immunogold labeling and transmission electron microscopy) of both angiopoietins 1&2, their receptor TIE2 as well as TIE1 to reveil the fnctional role of these molecules in intussesceptive angioensis.