Ultramicroscopic and molecular characteristics of the initial steps in intususceptive angiogensis: potential role of the angiopoietins and their receptors.

01 January 2013 → 31 October 2017
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Animal biology
    • Genetics
  • Agricultural and food sciences
    • Veterinary medicine
ultramicroscopy glomerulogenesis angiogenesis
Project description

Ultramicroscopic three-dimensional investigation of the initial steps of intussusceptive angiogenesis during glomerulogenesis in the porcine embryonic kidney. The morphological features are combined with the immunohistochemical detection and cellular localization (through immunogold labeling and transmission electron microscopy) of both angiopoietins 1&2, their receptor TIE2 as well as TIE1 to reveil the fnctional role of these molecules in intussesceptive angioensis.