Project

Improving risk-assessment in chilhood acute lymphoblastic leukaemia bij identification of a blood/bone marrow niRNA signature with prognostic value

Duration
01 January 2011 → 31 December 2014
Funding
Funding by bilateral agreement (private and foundations)
Promotor
Research disciplines
  • Natural sciences
    • Genetics
    • Systems biology
  • Medical and health sciences
    • Laboratory medicine
    • Medical systems biology
    • Molecular and cell biology
    • Laboratory medicine
    • Medical systems biology
    • Molecular and cell biology
    • Laboratory medicine
    • Medical systems biology
    • Molecular and cell biology
Keywords
childhood leukamia relapse prognostic microRNA
 
Project description

The aim of tis study is to improve the risk-stratification in childhood acute lymphoblastic leukemia to obtain a better treatment outcome,and aviod long lasting toxic side effects through preventing unnecessary and expensive treatment. We will evaluate the prognostic significance of miRNA gene expression in paediatric acute lymphblastic leukaemia (ALL) through miRNA expression profiling of bone marrow and serum samples.