Research Explorer

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Project

Targeting transcription factor addiction in acute leukemia (TaTFAL)

Outputs and Outcomes

Publications

Tet2 is a tumor suppressor in the pre-leukemic phase of T-cell acute lymphoblastic leukemia

Stien De ConinckJuliette RoelsBéatrice LintermansSara T'SasTom TaghonDavid CurtisTim PietersSteven GoossensPieter Van Vlierberghe

A1 Journal Article in BLOOD ADVANCES

Activation of goblet-cell stress sensor IRE1β is controlled by the mucin chaperone AGR2

Eva ClootsPhaedra GuilbertMathias ProvostLisa NeidhardtEvelien Van De VeldeFarzaneh FayazpourDelphine De SutterSavvas SavvidesSven EyckermanSophie Janssens

A1 Journal Article in EMBO JOURNAL

Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma

Stien De ConinckRenate De SmedtBéatrice LintermansLindy ReunesHansen J. KosasihAlexandra ReekmansLauren M. BrownNadine Van RoyBruno PalhaisJuliette RoelsMalaïka Van der LindenJo Van DorpePanagiotis NtziachristosFrederik W. Van DelftMarc R. MansourTim PietersTim LammensBarbara De MoerlooseCharles E. De BockSteven GoossensPieter Van Vlierberghe et al.

A1 Journal Article in HAEMATOLOGICA

Protein citrullination and NET formation do not contribute to the pathology of A20/TNFAIP3 mutant mice

Karel Van DammePieter HertensArne MartensElisabeth GilisDario PriemInge BruggemanAmelie FossoulJozefien DeclercqHelena Catharine AegerterAndy WullaertTino HochepiedEsther HosteLieselotte Vande WalleMohamed LamkanfiSavvas SavvidesDirk ElewautBart LambrechtGeert van Loo et al.

A1 Journal Article in SCIENTIFIC REPORTS

Pre-clinical evaluation of the hypomethylating agent decitabine for the treatment of T-cell lymphoblastic lymphoma

Lien ProvezTom PuttemanMattias LandforsJuliette RoelsLindy ReunesSara T'SasWouter Van LoockeBéatrice LintermansStien De ConinckMorgan ThenozWouter SleeckxNatalia Maćkowska-MaślakTom TaghonMarc R. MansourNadine FarahKoen NorgaPeter VandenbergheRishi S. KotechaSteven GoossensSofie DegermanRenate De SmedtPieter Van Vlierberghe et al.

A1 Journal Article in CANCERS