Research Explorer

Project

Exploration of the cellular and molecular functions of prognostic factors in chronic lymphocytic leukemia (CLL)
Code
3G099110
Duration
01 January 2010 → 31 December 2015
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Medical and health sciences
    • Laboratory medicine
    • Palliative care and end-of-life care
    • Regenerative medicine
    • Other basic sciences
    • Laboratory medicine
    • Palliative care and end-of-life care
    • Regenerative medicine
    • Other clinical sciences
    • Other health sciences
    • Nursing
    • Other paramedical sciences
    • Laboratory medicine
    • Palliative care and end-of-life care
    • Regenerative medicine
    • Other translational sciences
    • Other medical and health sciences
Keywords
electroporation CLL prognosis LPL ZAP70
 
Project description

There are numerous biological and clinical prognostic factors for CLL, which may predict early during the disease, the aggressiveness in an individual patient. MicroRNAs, LPL and ZAP70 are well known markers, but their cellular function in CLL is not well described. By electroporation we wish to better explore their functional relevance in CLL.