Code
01SC1312
Duration
01 March 2012 → 30 September 2016
Funding
Regional and community funding: Special Research Fund
Promotor
Fellow
Research disciplines
-
Natural sciences
- Microbiology
- Systems biology
-
Medical and health sciences
- Laboratory medicine
- Microbiology
- Laboratory medicine
- Laboratory medicine
- Microbiology
-
Agricultural and food sciences
- Fisheries sciences
Keywords
quorum sensing
gene expression
virulence genes
vibrio
shrimp
stress hormone
Project description
The virulence of luminescent vibrios is determined by the expression of different virulence genes. In this project, a model system with gnotobiotic brine shrimp (Artemia) larvae will be used to study virulence gene expression in vivo during infection. Furthermore, the impact of bacterial cell-to-cell communication (quorum sensing) and host stress hormones on virulence gene expression will be studied as well.