Project

Extracellular vesicle (EV) transport across the brain barriers: from mechanistic and biological insights towards strategies for delivery of therapeutics to the brain.

Duration
01 January 2021 → Ongoing
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Molecular biophysics
    • Proteins
    • Neurosciences not elsewhere classified
Keywords
Extracellular vesicles Brain barriers Drug delivery to the brain Photoporation
 
Project description

Extracellular vesicles (EVs) are nanosized membrane vesicles released by a broad range of cells. We study the mechanism by which EVs cross the central nervous system (CNS) barriers using innovative EV-loading technologies and surface proteome analysis. Next, we use this knowledge to develop novel brain targeting strategies for drug delivery.