Research Explorer

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Project

Cut-and-paste chemistry: from circular plastics to immunotherapeutics

Outputs and Outcomes

Publications

Dual-ligand PROTACS mediate superior target protein degradation in vitro and therapeutic efficacy in vivo

Yong ChenZihan XiaUjjwal SuwalPekka RappuJyrki HeinoOlivier De WeverBruno De Geest

A1 Journal Article in CHEMICAL SCIENCE

Thermoswitchable catalysis to inhibit and promote plastic flow in vitrimers

Filip Van LysebettenStephan MaesJohan WinneFilip Du Prez

A1 Journal Article in CHEMICAL SCIENCE

Thermally triggered triazolinedione-tyrosine bioconjugation with improved chemo- and site-selectivity

Elias DenijsKamil ÜnalKevin BevernaegeSabah KasmiBruno De GeestJohan Winne

A1 Journal Article in JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phenylpropynones as selective disulfide rebridging bioconjugation reagents

Diederick MaesMarvin NicqueMehwish IftikharJohan Winne

A1 Journal Article in ORGANIC LETTERS

Reprocessable polyurethane foams using acetoacetyl-formed amides

Hiba KassemLucie ImbernonLucas StrickerLaura JonckheereFilip Du Prez

A1 Journal Article in ACS APPLIED MATERIALS & INTERFACES

Sequence-defined antibody-recruiting macromolecules

Resat AksakalCorentin TonneauxAnnemiek UvynMathieu FossépréHatice TurgutNezha BadiMathieu SurinBruno De GeestFilip Du Prez

A1 Journal Article in CHEMICAL SCIENCE

Epoxy adhesives with reversible hardeners : controllable thermal debonding in bulk and at interfaces

Filip Van LysebettenTim MaiheuJohan WinneFilip Du Prez

A1 Journal Article in ADVANCED MATERIALS

N-sulfonyl urethanes to design polyurethane networks with temperature-controlled dynamicity

Stephan MaesFilip Van LysebettenJohan WinneFilip Du Prez

A1 Journal Article in MACROMOLECULES

Visible light conjugation with triazolinediones as a route to degradable poly(ethylene glycol)-lipids for mRNA lipid nanoparticle formulation

Bianka GolbaMatthieu SoeteZifu ZhongNiek SandersFilip Du PrezHannes HouckBruno De Geest

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recyclable vitrimer epoxy coatings for durable protection

Filip Van LysebettenStéphanie EngelenErwin BautersWim Van VoorenMaarten M. J. SmuldersFilip Du Prez

A1 Journal Article in EUROPEAN POLYMER JOURNAL

Polyaddition synthesis using alkyne esters for the design of vinylogous urethane vitrimers

Yann SpiesschaertJens DanneelsNiels Van HerckMarc GuerreGuillaume AckeJohan WinneFilip Du Prez

A1 Journal Article in MACROMOLECULES