Project

Pathways to pluripotency and differentiation in embryos and embryonic stem cells

Duration
01 January 2012 → 31 October 2018
Funding
Regional and community funding: Special Research Fund
Promotor
Research disciplines
  • Natural sciences
    • Animal biology
    • Genetics
  • Medical and health sciences
    • Gynaecology and obstetrics
    • Molecular and cell biology
    • Morphological sciences
    • Gynaecology and obstetrics
    • Molecular and cell biology
    • Morphological sciences
    • Gynaecology and obstetrics
    • Molecular and cell biology
    • Morphological sciences
  • Agricultural and food sciences
    • Veterinary medicine
Keywords
embryonic stem cells embryo human cattle
 
Project description

An embryo develops from a group of pluripotent cells into a differentiated organism. This transition from pluripotency to differentiation is dependent on the presence of transcription factors such as OCT 4 and NANOG. Also signaling molecules are involved and so are epigenetics. By means of transcriptome, epigenome and proteome analysis in embryos and embryonic stem cells, we aim to unravel the pathways involved this process.