Acronym
Role of Alveolar MFs
Code
41MC1212
Duration
01 March 2012 → 28 November 2016
Funding
European funding: framework programme
Promotor
Research disciplines
-
Medical and health sciences
- Immunology
- Respiratory medicine
- Immunology
- Microbiology
- Respiratory medicine
- Immunology
- Respiratory medicine
Keywords
kupffer cells
asthma
monocytes
dendritic cells
macrophages
immunoregulation
alveolar macrophages
Project description
Dendritic Cells (DCs) and MFs present antigens to T cells, which differentiate into Effector or Regulatory T cells. Some DCs or MFs may preferentially induce tolerance through Regulatory T cells, while others may preferentially induce Effector T cells. We will study the role of distinct DCs and MFs by restricting antigen-presenting-capacity to one DC or MF subset at a time.