Project

Study of the functional role of the distinct lung nd liver antigen-presenting cells subsets in vivo.

Acronym
Role of Alveolar MFs
Duration
01 March 2012 → 28 November 2016
Funding
European funding: framework programme
Research disciplines
  • Medical and health sciences
    • Immunology
    • Respiratory medicine
    • Immunology
    • Microbiology
    • Respiratory medicine
    • Immunology
    • Respiratory medicine
Keywords
kupffer cells asthma monocytes dendritic cells macrophages immunoregulation alveolar macrophages
 
Project description

Dendritic Cells (DCs) and MFs present antigens to T cells, which differentiate into Effector or Regulatory T cells. Some DCs or MFs may preferentially induce tolerance through Regulatory T cells, while others may preferentially induce Effector T cells. We will study the role of distinct DCs and MFs by restricting antigen-presenting-capacity to one DC or MF subset at a time.