Project

Quantum dot nanoparticles for live cell imaging and intracellular targeting.

Duration
01 October 2010 → 30 September 2016
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Applied mathematics in specific fields
    • Inorganic chemistry
  • Engineering and technology
    • Multimedia processing
    • Biomaterials engineering
    • Materials science and engineering
    • Biological system engineering
    • Biomaterials engineering
    • Biomechanical engineering
    • Other (bio)medical engineering
    • Environmental engineering and biotechnology
    • Industrial biotechnology
    • Other biotechnology, bio-engineering and biosystem engineering
    • Signal processing
Keywords
cell labeling fluorescence microscopy quantum dots
 
Project description

This project is aimed at enabling fluorescent labeling of organelles in living cells by quantum dots. At the one hand, silica encapped quantum dots will be targeted to the cytosol by making use of a membrane-disruptive liposomal carrier. At the other hand, a new concept will be tested using thermoresponsive nanoparticles to enable endosomal escape to the cytosol.