Research Explorer

Project

Characterizing a rupture-prone mouse model of aortic aneurysm: the road to post-mortem validation of AAA rupture risk predicted by biomechanical computational models
Code
01P11013
Duration
01 October 2013 → 30 September 2017
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Biomechanics
    • Cardiac and vascular medicine
    • Biomechanics
    • Cardiac and vascular medicine
    • Biomechanics
    • Cardiac and vascular medicine
Keywords
aneurysm mouse model rupture
 
Project description

Abdominal aortic aneurysm (AAA) is a local dilatation of the aorta that can lead to sudden death when it ruptures. Patients are currently operated when the aneurysmatic diameter exceeds 5.5 cm. In this project, we want to investigate whether numerical techniques can characterize and predict the actual rupture incidence and location in a novel, rupture-prone mouse model of the disease.