Research Explorer

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Project

Enhancing DNA vaccine efficacy by coexpression of viral antigen and cell death modulating proteins

Outputs and Outcomes

Code

12CE0108

Duration

15 August 2008 → 15 June 2009

Funding

Federal funding: various

Promotor

Peter Vandenabeele

Research disciplines

Medical and health sciences
- Immunology
- Immunology
- Microbiology
- Immunology

Keywords

nucleoprotein necrosis apoptosis

Project description

DNA vaccination is a promissing technique to induce cellular immune responses against an anitgen of interest. However clinical applications of DNA vaccination still suffer from poor immune responses. The aim of this project is to determine if the coexpression of a viral antigen and cell death modulating adaptor proteins can enhance the immune response as well as protection against a homologous viral challenge.

English

Dutch

English

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