15 August 2008 → 15 June 2009
Federal funding: various
Medical and health sciences
nucleoprotein necrosis apoptosis
DNA vaccination is a promissing technique to induce cellular immune responses against an anitgen of interest. However clinical applications of DNA vaccination still suffer from poor immune responses. The aim of this project is to determine if the coexpression of a viral antigen and cell death modulating adaptor proteins can enhance the immune response as well as protection against a homologous viral challenge.