Code
3E009507
Duration
01 October 2007 → 30 September 2015
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Promotor
Fellow
Research disciplines
-
Natural sciences
- Biochemistry and metabolism
- Systems biology
-
Medical and health sciences
- Medical biochemistry and metabolism
- Medical biochemistry and metabolism
- Medical biochemistry and metabolism
-
Engineering and technology
- Biomaterials engineering
- Biological system engineering
- Biomaterials engineering
- Biomechanical engineering
- Other (bio)medical engineering
- Environmental engineering and biotechnology
- Industrial biotechnology
- Other biotechnology, bio-engineering and biosystem engineering
Keywords
F-box proteins
N-glycosylation
lectins
Project description
In animal models, it has been shown that N-glycosylation can be a prerequisite for targeting of glycoproteins for degradation. In this process sugar-binding F-box proteins (or Fbs proteins) are involved. Homologous nucleocytoplasmic F-box proteins have been discovered in plants. In this project, putative Fbs proteins from plants will be functionally characterized and compared with the animal Fbs proteins.