Project

Automated production and expansion of cell therapy products

Acronym
AUTOPROCELL
Code
F2023/IOF-Equip/071
Duration
20 December 2023 → 19 December 2025
Funding
Regional and community funding: Industrial Research Fund
Promotor
Research disciplines
  • Engineering and technology
    • Cellular therapy
Keywords
Blood stem cells T cell precursors oxygen automated cellular expansion closed bioreactor
 
Project description

Blood forming stem cells and gene-engineered (CAR) T cells are frequently used cell therapy producs in todays medicine. Their application is however hampered by the immense costs that are associated with their isolation, manipulation and culture since this needs to be done for each patient specifically. In this project, we wish to use a clinical-compatible instrument in which the culture conditions of these cell types will be tweaked, based on specific scientific knowledge, to improve their production at both the quantitative and qualitative level. This will vastly improve the broad clinical implementation of these cell therapy products.