Research Explorer

Project

The influence of cigarette smoke on the innate and adaptive intestinal immune response and on the pathogenesis of Crohn's disease.
Code
01D21009
Duration
01 October 2009 → 30 September 2011
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Gastro-enterology and hepatology
    • Laboratory medicine
    • Gastro-enterology and hepatology
    • Laboratory medicine
    • Gastro-enterology and hepatology
    • Laboratory medicine
Keywords
Peyer's patches cigarette smoke crohn's disease
 
Project description

Peyer's patches play an important role in the development of the normal mucosal immune response furthermore this is the region where first manifestations of Crohn's desease (CD) occur. Smoking has a detrimental role in CD pathogenesis we want to investigate the influence of cigarette smoke on mucosal immunity and receal how this can lead to the development of CD