The TIE receptors are an important regulator of blood vessel growth and homeostasis. They are indispensable molecules involved in angiogenesis and participate in processes related to cell survival, cell mobility and cell proliferation. Recent studies show that they are present on various cells such as pericytes, macrophages or cancer cells. In our laboratory, we observed the expression of the TIE receptors in glomerular podocytes of the kidney. With this PhD work we further characterize the localization and function of the TIE-receptors in podocytes. This is performed by means of in vitro cell culture experiments and super resolution microscopy.