Project

Quorum quenching as a novel tool to fight bacterial infections in aquaculture

Duration
01 October 2010 → 30 September 2014
Funding
Research Foundation - Flanders (FWO)
Promotor
Research disciplines
  • Natural sciences
    • Microbiology
    • Systems biology
  • Medical and health sciences
    • Laboratory medicine
    • Microbiology
    • Laboratory medicine
    • Laboratory medicine
    • Microbiology
Keywords
aquaculture quorum sensing microbiology
 
Project description

In many bacteria, the production of virulence factors is controlled by quorum sensing (QS) and interfering with QS has been proposed as a new strategy to fight infections in aquaculture. Increasing attention is being paid to quorum quenching (QQ), the degradation of QS molecules by bacterial enzymes. The goal of the project is to isolate QS degrading organisms, construct mutants with high QQ activity, and evaluate the effect of QS degrading strains.