Research Explorer

Project

No pain, just gain: new dried blood microsample-based avenues for steroid testing
Code
01D30222
Duration
01 October 2022 → 30 September 2026
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Separation techniques
    • Spectrometry
    • Analytical toxicology
    • Clinical toxicology
    • Endocrinology
Keywords
Automated DBS (dried blood spot) analysis Anabolic androgenic steroids (AAS) Hematocrit prediction LC-MS/MS Volumetric absorptive microsampling (VAMS) Microsampling
 
Project description

For decades, anabolic androgenic steroids have been the most commonly abused substances in sports. This project aims at optimizing fully validated LC-MS/MS methods for steroid determination in dried blood microsamples, including dried blood spots (DBS) and samples collected by volumetric absorptive microsampling (VAMS). A fully automated DBS method will be developed, allowing analysis of a steroid panel.