Research Explorer

Project

Transposable elements-mediated gene regulatory networks of brain diseases
Code
01D29922
Duration
01 October 2022 → 30 September 2026
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Analysis of next-generation sequence data
    • Bioinformatics data integration and network biology
    • Bioinformatics of disease
    • Computational transcriptomics and epigenomics
    • Single-cell data analysis
Keywords
Bioinformatics pipeline Multi-omics Bioinformatics of disease Bioinformatics data integration and network biology Single-cell data analysis Schizophrenia Glioblastoma multiforme
 
Project description
 

In recent years, it has become clear that transposable elements are not just part of the ‘junk’ DNA, but exert several functions and are implicated in several human diseases. Through using multi-omics data and gene regulatory networks, we will elucidate the role of transposable elements in the brain diseases schizophrenia and glioblastoma multiforme, for which effective treatment is still lacking.