Code
01D28622
Duration
01 October 2022 → 31 October 2023
Funding
Regional and community funding: Special Research Fund
Promotor
Fellow
Research disciplines
-
Medical and health sciences
- Microbiome
- Cell signalling
- Cellular interactions and extracellular matrix
- Cancer biology
- Cancer therapy
Keywords
Bacterial extracellular vesicles
gut microbiota
cancer immunology
Project description
Bacteria release bacterial extracellular vesicles (BEV), membrane-enclosed particles that contain
biomolecules, and can be recognized by the immune system. The discovery that BEV are present in
the blood circulation of cancer patients with impaired intestinal barrier integrity sparks interest in
unraveling the immune biological role of BEV, since they are hypothesized to influence the patient's
immune activity and therapy response.