Research Explorer

Project

Source-driven metabolome prediction towards 3P medicine in children
Code
01D16222
Duration
01 October 2022 → 31 October 2023
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Food chemistry
  • Medical and health sciences
    • Medical metabolomics
    • Metabolic diseases
    • Medical biochemistry and metabolism not elsewhere classified
    • Paediatrics
Keywords
Metabolomics Pediatric obesity Source-driven metabotypes 3P medicine
 
Project description
 

Source-driven metabolite predictions (based on diet, microbiome, …) for children with obesity will be proposed, providing a basis towards individualization of treatments (3P principle). For this purpose, various (metabolic) data from 4 pediatric cohorts (n = 1412) will be included in machine learningbased prediction models. Next, this will be brought into routine clinical practice with the help of a patented sampler.