Research Explorer

Project

Study for the role of type I and III interferons in endotoxemia and sepsis
Code
3F014507
Duration
01 October 2007 → 31 May 2010
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Research disciplines
  • Medical and health sciences
    • Laboratory medicine
    • Palliative care and end-of-life care
    • Regenerative medicine
    • Other basic sciences
    • Laboratory medicine
    • Palliative care and end-of-life care
    • Regenerative medicine
    • Other clinical sciences
    • Other health sciences
    • Nursing
    • Other paramedical sciences
    • Laboratory medicine
    • Palliative care and end-of-life care
    • Regenerative medicine
    • Other translational sciences
    • Other medical and health sciences
Keywords
sepsis interferon mouse
 
Project description
 

I will investigate if type I and III interferons are involved in sepsis and endotoxemia. I will investigate if type I and III IFNs play a role in gram negative and positive infection. Therefore, I will use the IFNAR1-/- and IL28Ra-/- mouse, a neutralising IFN-B or IFNAR1 antibody and expressionstudies.