Research Explorer

Project

Cystic fibrosis as a modulable model for mucosal and systemic immunity in airway disease.
Code
01D07022
Duration
01 October 2022 → 31 October 2022
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Inflammation
    • Immunology not elsewhere classified
    • Respiratory medicine
Keywords
Cystic fibrosis (CF) Airway Inflammation Host – micro-organism interactions
 
Project description

CFTR modulation equilibrates airway inflammation and systemic immune responses in CF patients. Blood and sputum samples are collected pre-/post-CFTR modulation into our prospective biobank. We will assess the role of CFTR in airway microenvironment and host immune response. CF patients will serve as the basis to study airway inflammation and host–microorganism interactions in the context of chronic microbial exposure.