Project

Influence of dosage, administration route and intestinal health on antibacterial resistance selection in pig intestinal commensal flora and optimization of dosage regimen of selected antibacterial drugs.

Duration
01 January 2015 → 30 June 2018
Funding
Federal funding: various
Research disciplines
  • Agricultural and food sciences
    • Veterinary medicine not elsewhere classified
Keywords
administration route dosage resistance pigs antimicrobials
 
Project description

The posology of currently available antimicrobials was determined solely based on clinical efficacy and outcome, without taking resistance selection into account. The goal of present study is to evaluate the effect of dosage (over- and underexposure), route of administration (oral and parental) and intestinal health (inflammation) on resistance selection in the commensal microbiota of pigs.