Research Explorer

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Project

It takes two to tango_ a decryption of Marfan cardiomyopathy using human iPSC- derived cardiac cells and engineered heart tissues

Outputs and Outcomes

Publications

Developing a global education hub for animal-free innovation

Monique R. E. JanssensDaniela SalvatoriJanneke HogervorstCristheena NonisJarrod BaileyJeffrey BajramovicAnne BurgersFrancesca CaloniElza D. van DeelJanny van den Eijnden-van RaaijHossein E. AmirabadiDilyana FilipovaAnnalisa GastaldelloSusan GibbsBirgit GoversenNicole GreenJolanda van HengelAnne KienhuisSjoukje van de KolkCarlo A. PaggiLouis C. PenningFrancesca PistollatoSilke RieggerMerel Ritskes-HoitingaMaria P. Vinardell et al.

Editorial material

Human stem cell models for Marfan syndrome : a brief overview of the rising star in disease modelling

Jeffrey AaldersLaura Muiño MosqueraJolanda van Hengel

A1 Journal Article in FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

Improving cardiac differentiation of human pluripotent stem cells by targeting ferroptosis

Jeffrey AaldersLaurens LégerBehrouz HassanniaVera GoossensTom Vanden BergheJolanda van Hengel

A1 Journal Article in REGENERATIVE THERAPY

Three-dimensional co-culturing of stem cell-derived cardiomyocytes and cardiac fibroblasts reveals a role for both cell types in Marfan-related cardiomyopathy

Jeffrey AaldersLaurens LégerLouis Van der MeerenSanjay SinhaAndre SkirtachJulie De BackerJolanda van Hengel

A1 Journal Article in MATRIX BIOLOGY