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Natural sciences
- Inorganic chemistry
- Macromolecular and materials chemistry
The main objective of my proposal is obtaining stimuli-responsive molecularly imprinted poly(2- oxazoline)s and presenting their application in targeted drug delivery. The obtained polymers will be biocompatible poly(2-oxazoline)s, a polymer that is well-known for its biocompatibility. Moreover, the obtain material will release drug molecules only when a particular stimuli is applied. More precisely, I am planning to obtain polymers that will release drug molecules after illumination with a light or when a temperature will rise up to certain value. As drugs that will be delivered with the use of described polymers I am going to use anti-cancer drugs (doxorubicin, paclitaxel, 5-fluorouracil). The drug delivery system releasing drugs after interaction with light will be similar to currently us