Project

Synthesis and biological assessment of novel β-lactamase inhibitors in the framework of tuberculosis therapy in India

Code
01W04218
Looptijd
01-10-2018 → 30-09-2022
Financiering
Regional and community funding: Special Research Fund
Onderzoeksdisciplines
  • Natural sciences
    • Organic chemistry not elsewhere classified
    • Microbiology not elsewhere classified
    • Systems biology not elsewhere classified
  • Medical and health sciences
    • Laboratory medicine not elsewhere classified
    • Microbiology not elsewhere classified
    • Laboratory medicine not elsewhere classified
    • Laboratory medicine not elsewhere classified
    • Microbiology not elsewhere classified
Trefwoorden
Tuberculose India Organische synthese Biologische evaluatie β-lactamen
 
Projectomschrijving

Tuberculosis (TB) is an infectious disease responsible for 220.000 deaths per year in India, imposing an immense burden on the country’s health care system. This project aims at establishing an innovative approach in anti-TB therapy by designing β-lactamase inhibitors that could allow classical
β-lactam antibiotics to exert their antibacterial action against (resistant) Mycobacterium tuberculosis strains.