Code
01W04218
Duration
01 October 2018 → 30 September 2022
Funding
Regional and community funding: Special Research Fund
Promotor
Research disciplines
-
Natural sciences
- Organic chemistry not elsewhere classified
- Microbiology not elsewhere classified
- Systems biology not elsewhere classified
-
Medical and health sciences
- Laboratory medicine not elsewhere classified
- Microbiology not elsewhere classified
- Laboratory medicine not elsewhere classified
- Laboratory medicine not elsewhere classified
- Microbiology not elsewhere classified
Keywords
Tuberculosis
India
Organic synthesis
Biological evaluation
β-lactams
Project description
Tuberculosis (TB) is an infectious disease responsible for 220.000 deaths per year in India, imposing an immense burden on the country’s health care system. This project aims at establishing an innovative approach in anti-TB therapy by designing β-lactamase inhibitors that could allow classical
β-lactam antibiotics to exert their antibacterial action against (resistant) Mycobacterium tuberculosis strains.