Project

Manipulating cell fate during embryonic development and stem cell derivation

Duration
01 October 2012 → 30 September 2016
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Animal biology
    • Genetics
  • Medical and health sciences
    • Endocrinology and metabolic diseases
    • Gynaecology and obstetrics
    • Endocrinology and metabolic diseases
    • Gynaecology and obstetrics
    • Nursing
    • Endocrinology and metabolic diseases
    • Gynaecology and obstetrics
  • Agricultural and food sciences
    • Veterinary medicine
Keywords
embryos stem cells differentiation
 
Project description

The first differentiation of the embryo occurs at the blastocyst stage with the formation of the trophectoderm and inner cell mass. Subsequently, the inner cell mass forms the hypoblast and epiblast. By the use of small molecules, these segregations can be influenced. Question remains how this affects embryonic stem cell derivation.