Research Explorer

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Project

Investigating the protective role of the glucocorticoid receptor against lactate-mediated lethal shock in sepsis

Outputs and Outcomes

Publications

Unraveling mitochondrial pyruvate dysfunction to mitigate hyperlactatemia and lethality in sepsis.

Louise NuyttensMarah HeyerickGeike HeremansElise MoensMaxime RoesCéline Van DenderLiesbet De BusJohan DecruyenaereJan DewaeleJolien VandewalleClaude Libert et al.

U Journal Article in Cell reports

Generation of a new Paneth cell-specific Cre-recombinase transgenic mouse line

Natalia Garcia GonzalezCharlotte WallaeysWendy ToussaintTino HochepiedSylviane DewaeleSomara De BeulRobin Van LokeJolien VandewalleSteven TimmermansClaude Libert

U Journal Article in FRONTIERS IN IMMUNOLOGY

Modulation of glucocorticoid receptor function under iron overload

Wanting ZhuTineke VanderhaeghenSteven TimmermansJolien VandewalleMelanie EggermontNicolette J. D. VerhoogClaude Libert

U Journal Article in FRONTIERS IN IMMUNOLOGY

Comparative analysis of hepatic gene expression profiles in murine and porcine sepsis models

Fëllanza HalimiTineke VanderhaeghenSteven TimmermansSiska CroubelsClaude LibertJolien Vandewalle

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sepsis-induced changes in pyruvate metabolism : insights and potential therapeutic approaches

Louise NuyttensJolien VandewalleClaude Libert

A1 Journal Article in EMBO MOLECULAR MEDICINE

Microbial metabolome in septic shock : bridging bench to bedside

Jolien VandewalleClaude Libert

Editorial material

Spns2/S1P : it takes two to tango with inflammation and metabolic rewiring during sepsis

Tineke VanderhaeghenJolien VandewalleClaude Libert

Editorial material