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Project
Investigating the protective role of the glucocorticoid receptor against lactate-mediated lethal shock in sepsis
Information
Project Team
Organisations
Outputs and Outcomes
Publications
Unraveling mitochondrial pyruvate dysfunction to mitigate hyperlactatemia and lethality in sepsis.
Louise Nuyttens
Marah Heyerick
Geike Heremans
Elise Moens
Maxime Roes
Céline Van Dender
Liesbet De Bus
Johan Decruyenaere
Jan Dewaele
Jolien Vandewalle
Claude Libert
et al.
U
Journal Article
in
Cell reports
2025
Generation of a new Paneth cell-specific Cre-recombinase transgenic mouse line
Natalia Garcia Gonzalez
Charlotte Wallaeys
Wendy Toussaint
Tino Hochepied
Sylviane Dewaele
Somara De Beul
Robin Van Loke
Jolien Vandewalle
Steven Timmermans
Claude Libert
U
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2025
Modulation of glucocorticoid receptor function under iron overload
Wanting Zhu
Tineke Vanderhaeghen
Steven Timmermans
Jolien Vandewalle
Melanie Eggermont
Nicolette J. D. Verhoog
Claude Libert
U
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2025
Comparative analysis of hepatic gene expression profiles in murine and porcine sepsis models
Fëllanza Halimi
Tineke Vanderhaeghen
Steven Timmermans
Siska Croubels
Claude Libert
Jolien Vandewalle
A1
Journal Article
in
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2024
Sepsis-induced changes in pyruvate metabolism : insights and potential therapeutic approaches
Louise Nuyttens
Jolien Vandewalle
Claude Libert
A1
Journal Article
in
EMBO MOLECULAR MEDICINE
2024
Microbial metabolome in septic shock : bridging bench to bedside
Jolien Vandewalle
Claude Libert
Editorial material
2024
Spns2/S1P : it takes two to tango with inflammation and metabolic rewiring during sepsis
Tineke Vanderhaeghen
Jolien Vandewalle
Claude Libert
Editorial material
2023