Project

Synthetic strategies for the rapid assembly of evolutionary conserved terpene scaffolds

Duration
01 January 2017 → 31 October 2021
Funding
Regional and community funding: Special Research Fund
Promotor
Research disciplines
  • Natural sciences
    • Organic chemistry
Keywords
organic synthesis biology oriented synthesis natural products
 
Project description

New chemical strategies are explored for the assembly of complex terpene-like scaffolds, using simple starting materials. Terpenes are common metabolites with interesting biological activitities, sharing conserved structural features related to their evolutionary genesis. The possibility to modularly prepare unnatural derivatives of these natural products, will allow a much faster identification of new biologically potent compounds and biological pathways.