Evaluation of highly immunogenic tumor cell vaccines in combination with regulatory T-cell depletion

01 October 2011 → 30 September 2016
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Animal biology
  • Medical and health sciences
    • Morphological sciences
    • Oncology
    • Morphological sciences
    • Oncology
    • Morphological sciences
    • Oncology
  • Engineering and technology
    • Chemical product design and formulation
    • Biomaterials engineering
  • Agricultural and food sciences
    • Veterinary medicine
    • Other veterinary sciences
    • Other agricultural, veterinary and food sciences
tumor cells vaccination cancer
Project description

The aim of this project is to enhance the efficacy of tumor cell vaccines by increasing their immunogenicity and by combining the tumor cell vaccines with a depletion of regulatory T-cells. We will optimize this new vaccination strategy in tumor bearing mice. Subsequently, the most effective cancer vaccination protocol will be evaluated in dogs with cancer.