Project

Double-lumen branched catheter with perforations for intraperitoneal drug delivery

Acronym
Branched catheter
Code
F2022/IOF-StarTT/034
Duration
15 July 2022 → 14 July 2025
Funding
Regional and community funding: Industrial Research Fund
Promotor
Research disciplines
  • Medical and health sciences
    • Cancer therapy
  • Engineering and technology
    • Biomaterials engineering not elsewhere classified
    • Biomedical modelling
Keywords
catheter peritoneal metastasis carcinomatosis oncology intraperitoneal drug delivery cancer
 
Project description

The aim of this project is to develop a novel, multi-arm catheter for intraperitoneal drug delivery to treat patients with peritoneal metastases. This innovated design would allow:

Better spatial drug distribution (increases the surface exposure);

Prolonged, low dose (metronomic) chemotherapy administration;

To avoid intraperitoneal instillation of large volumes, thus avoiding side effects (pain, bloating) and reduce the incidence of resistance development.

Therefore, when the proposed catheter design proves to be superior in terms of anticancer efficacy, we expect that significant patient numbers may benefit from this novel device.