Research Explorer

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Project

Development and functional validation of a gene editing approach in hematopoietic precursor cells for Wiskott-Aldrich Syndrome

Outputs and Outcomes

Publications

ThymoSpheres culture : a model to study human polyclonal unconventional T cells

Lore BillietHanne JansenMelissa PilleLena BoehmeGuillem Sanchez SanchezLaurenz De CockGlenn GoetgelukEva PascalStijn De MunterLucas DeseinsJoline IngelsThomas MichielsRobrecht De VosAmin ZolfaghariNiels VandammeJana RoelsTessa KerreRuslan DmitrievTom TaghonDavid VermijlenBart Vandekerckhove et al.

A1 Journal Article in EUROPEAN JOURNAL OF IMMUNOLOGY

Neoantigen-targeted dendritic cell vaccination in lung cancer patients induces long-lived T cells exhibiting the full differentiation spectrum

Joline IngelsLaurenz De CockDieter StevensRupert MayerFabien Henri TheryGuillem Sanchez SanchezDavid VermijlenKarin WeeningSaskia De SmetNele LootensMarieke BrusseelTasja VerstraeteJolien BuyleEva Van HouttePam DevrekerKelly HeynsStijn De MunterSandra Van LintGlenn GoetgelukSarah BonteLore BillietMelissa PilleHanne JansenEva PascalLucas DeseinsLies VantommeMaarten VerdoncktRia RoelandtThomas EekhoutNiels VandammeGeorges LeclercqTom TaghonTessa KerreFloris VanommeslaegheAnnemieke DhondtLiesbeth FerdinandeJo Van DorpeLiesbeth DesenderFrederic De RyckFrank VermassenVeerle SurmontFrancis ImpensBjörn MentenKarim VermaelenBart Vandekerckhove et al.

A1 Journal Article in CELL REPORTS MEDICINE

Gene editing-based targeted integration for correction of Wiskott-Aldrich syndrome

Melissa PilleJohn M. AvilaSo Hyun ParkCuong Q. LeHaipeng XueFilomeen HaerynckLavanya SaxenaCiaran LeeElizabeth J. ShpallGang BaoBart VandekerckhoveBrian R. Davis et al.

A1 Journal Article in MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT

The Wiskott–Aldrich syndrome protein is required for positive selection during T-cell lineage differentiation

Melissa PilleJohn AvilaGuillem Sanchez SanchezGlenn GoetgelukStijn De MunterHanne JansenLore BillietKarin WeeningHaipeng XueSarah BonteJoline IngelsLaurenz De CockEva PascalLucas DeseinsTessa KerreTom TaghonGeorges LeclercqDavid VermijlenBrian DavisBart Vandekerckhove et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY