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Project

Development of novel assays to characterize the size and dynamics of the HIV-1 viral reservoir.

Information

Project Team

Outputs and Outcomes

Publications

Potent latency reversal by Tat RNA-containing nanoparticle enables multi-omic analysis of the HIV-1 reservoir

Marion PardonsBasiel ColeLaurens LambrechtsWillem van SnippenbergSofie RutsaertYtse NoppeNele De LangheAnnemieke DhondtJerel VegaFilmon EyassuErik NijsEllen Van GulckDaniel BodenLinos Vandekerckhove et al.

A1 Journal Article in NATURE COMMUNICATIONS

2023

HIV-PULSE : a long-read sequencing assay for high-throughput near full-length HIV-1 proviral genome characterization

Laurens LambrechtsNoah BonineRita VerstraetenMarion PardonsYtse NoppeSofie RutsaertFilip Van NieuwerburghWim Van CriekingeBasiel ColeLinos Vandekerckhove

A1 Journal Article in NUCLEIC ACIDS RESEARCH

2023

Extensive characterization of HIV-1 reservoirs reveals links to plasma viremia before and during analytical treatment interruption

Basiel ColeLaurens LambrechtsZoe BoyerYtse NoppeMarie-Angélique De ScheerderJohn-Sebastian EdenBram VranckenTimothy E. SchlubSherry McLaughlinLisa M. FrenkelSarah PalmerLinos Vandekerckhove et al.

A1 Journal Article in CELL REPORTS

2022