Research Explorer

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Project

A profound study of gut homeostasis in Parkinson's disease.

Outputs and Outcomes

Publications

Safety and efficacy of faecal microbiota transplantation in patients with mild to moderate Parkinson's disease (GUT-PARFECT) : a double-blind, placebo-controlled, randomised, phase 2 trial

Arnout BruggemanCharysse VandendriesscheHannelore HamerlinckDanny De LoozeDavid J. TateMarnik VuylstekeLindsey De CommerLindsay DevolderJeroen RaesBruno VerhasseltDebby LaukensRoosmarijn VandenbrouckePatrick Santens et al.

A1 Journal Article in ECLINICALMEDICINE

The spreading and effects of human recombinant α-synuclein preformed fibrils in the cerebrospinal fluid of mice

Charysse VandendriesscheArnout BruggemanJoyce ForoozandehLien Van HoeckePieter DujardinJunhua XieGriet Van ImschootElien Van WonterghemJonas CasteleinCristiano LucciLies De GroefRoosmarijn Vandenbroucke et al.

A1 Journal Article in ENEURO

Gut microbiota regulates blood-cerebrospinal fluid barrier function and Aβ pathology

Junhua XieArnout BruggemanClint De NolfCharysse VandendriesscheGriet Van ImschootElien Van WonterghemLars VereeckeRoosmarijn Vandenbroucke

A1 Journal Article in EMBO JOURNAL

Influence of probiotic bacteria on gut microbiota composition and gut wall function in an in-vitro model in patients with Parkinson's disease

Jonas GhyselinckLynn VerstrepenFrédéric MoensPieter Van Den AbbeeleArnout BruggemanJawal SaidBarry SmithLynne Ann BarkerCaroline JordanValentina LetaK. Ray ChaudhuriAbdul W. BasitSimon Gaisford et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF PHARMACEUTICS-X

Posttraumatic functional movement disorders and litigation

Patrick SantensArnout Bruggeman

A1 Journal Article in ACTA NEUROLOGICA BELGICA

Reversible drug‐induced Pisa syndrome due to a cholinesterase inhibitor

Arnout BruggemanLucas LevrauPatrick Santens

Editorial material

Anti-inflammatory mesenchymal stromal cell-derived extracellular vesicles improve pathology in Niemann-Pick type C disease

Lien Van HoeckeCaroline Van CauwenbergheVerena BoergerArnout BruggemanJonas CasteleinGriet Van ImschootElien Van WonterghemRobin DittrichWouter ClaeysJunhua XieBernd GiebelRoosmarijn Vandenbroucke et al.

A1 Journal Article in BIOMEDICINES

Gastric Helicobacter suis infection partially protects against neurotoxicity in A 6-OHDA Parkinson’s disease mouse model

Helena BerlamontArnout BruggemanEva BauwensCharysse VandendriesscheElien ClareboutJunhua XieSofie De BruyckereGriet Van ImschootElien Van WonterghemRichard DucatellePatrick SantensAnnemieke SmetFreddy HaesebrouckRoosmarijn Vandenbroucke et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Importance of extracellular vesicle secretion at the blood-cerebrospinal fluid interface in the pathogenesis of Alzheimer’s disease

Charysse VandendriesscheSriram BalusuCaroline Van CauwenbergheMarjana BrkićMarie PauwelsNele PlehiersArnout BruggemanPieter DujardinGriet Van ImschootElien Van WonterghemAn HendrixFemke BaekeRiet De RyckeKris GevaertRoosmarijn Vandenbroucke et al.

A1 Journal Article in ACTA NEUROPATHOLOGICA COMMUNICATIONS

Extracellular vesicles in Alzheimer's and Parkinson's disease : small entities with large consequences

Charysse VandendriesscheArnout BruggemanCaroline Van CauwenbergheRoosmarijn Vandenbroucke

A1 Journal Article in CELLS