Molecular and functional analysis of regulatory globins in Caenorhabditis elegans

01 October 2009 → 30 September 2013
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Animal biology
    • Biochemistry and metabolism
    • General biology
    • Systems biology
  • Medical and health sciences
    • Medical biochemistry and metabolism
    • Medical biochemistry and metabolism
    • Medical biochemistry and metabolism
  • Agricultural and food sciences
    • Veterinary medicine
globins physiology caenorhabditis elegans
Project description

Any functional knowledge of the 33 globins that are encoded by the C. elegans genome is almost non-existent. We plan perform a functional analysis of globin-12, of which the mutant shows a sterile phenotype, and globin-33 that consists of a linked globin and GPCR domain. For this study, we will apply biochemical, biophysical, physiological and molecular techniques.