Project

Probiotic administration as add-on therapy in ulcerative colitis and pouchitis

Duration
01 October 2007 → 30 September 2011
Funding
Regional and community funding: IWT/VLAIO
Research disciplines
  • Natural sciences
    • Microbiology
    • Systems biology
  • Medical and health sciences
    • Gastro-enterology and hepatology
    • Laboratory medicine
    • Microbiology
    • Gastro-enterology and hepatology
    • Laboratory medicine
    • Gastro-enterology and hepatology
    • Laboratory medicine
    • Microbiology
Keywords
probiotics bifidobacterium IBD
 
Project description

A probiotic strain (Bifidobacterium breve UCP0911) was selected with anti-inflammatory properties and hence, important potential in the treatment of inflammatory bowel disease (IBD). During well-designed clinical trials, the potential of the selected probiotic in IBD patients (ulcerative colitis and pouchitis) will be fully explored. These clinical trials will aim at unravelling the basic interaction between microbial, immunological and genetic parameters in correlation with the clinical outcome, based on a rational multidisciplinary approach.