Research Explorer

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Project

Study of RIP4 kinase function in cancer

Outputs and Outcomes

Code

365O4510

Duration

01 January 2011 → 31 December 2015

Funding

Funding by bilateral agreement (private and foundations)

Promotor

Wim Declercq

Research disciplines

Medical and health sciences
- Dermatology
- Morphological sciences
- Oncology
- Dermatology
- Morphological sciences
- Oncology
- Dermatology
- Morphological sciences
- Oncology

Keywords

cancer NF-kB RIP kinases

Project description

RIP (receptor interacting protein) 4 kinase is implicated in activation of the transcription factors NF-B and AP-1. Both transcription factors are often aberrantly regulated in several cancer types. Interestingly, recently RIP4K mutants were identified in different cancer types. Therefore, we will study the role of RIP4 in cancer.

English

Dutch

English

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