Research Explorer

Project

Advanced biosystems modeling: a holistic approach incorporating submodel balancing, model structure sensitivity analysis and experimental identifiability
Code
01D38910
Duration
01 October 2010 → 30 September 2014
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Applied mathematics in specific fields
    • Computer architecture and networks
    • Distributed computing
    • Information sciences
    • Information systems
    • Programming languages
    • Scientific computing
    • Theoretical computer science
    • Visual computing
    • Other information and computing sciences
  • Medical and health sciences
    • Biomechanics
    • Biomechanics
    • Biomechanics
  • Engineering and technology
    • Sustainable and environmental engineering
Keywords
balancing submodels model structure sensitivity analysis uncertainty propagation experimental identifiability biosystems modeling
 
Project description
 

Advanced mathematical models are necessary to optimize the currently used suboptimal biosystems. However, when constructing these models, often a mismatch between spatial and bioprocess description occurs. This project develops novel mathematical methodological concepts (model structure sensitivity analysis, uncertainty propagation, experimental identifiability) in order to restore the balance between submodels taking into account experimental data availability.