Project

The interactions between the brain and MMP8 and MMP3 in systemic inflammation

Duration
01 January 2012 → 31 December 2017
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Social sciences
    • Biological and physiological psychology
    • Cognitive science and intelligent systems
    • Developmental psychology and ageing
  • Medical and health sciences
    • Immunology
    • Neurosciences
    • Immunology
    • Neurosciences
    • Immunology
    • Neurosciences
Keywords
sepsis mechanisms brain
 
Project description

During systemic inflammation, eg in sepsis patients, a certain degree of neuronal complications can be observed, ranging from very mild to very severe (e.g. coma). In this project, we want to investigate the molecular mechanism of this phenomenon focusing on MMP3 and MMP8, two proteases.