Cationic gold-catalyzed cyclizations for the preparation of complex azaheterocycles

01 October 2015 → 31 December 2016
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Inorganic chemistry
    • Organic chemistry
catalysis homogeneous gold azaheterocyclic vinylidene enyne cyclization ligands
Project description

Cationic homogeneous Au(I)-catalysts will be evaluated for the synthesis of complex N-containing cyclic compounds. Firstly, both intra- and intermolecular 1,n-enyne cyclizations will be studied, where the attack of a N-nucleophile is crucial. Secondly, the reaction between in situ formed Au-vinylidenes and N-nucleophiles will be investigated.